Process Scale Chromatography (PSC) Systems
Process scale chromatography is a large-scale manufacturing technique used to purify and isolate biomolecules and other chemicals in a process environment.
Regular preventive maintenance (PM) of your process scale chromatography equipment is the most efficient way of ensuring optimal performance and reliability. The most complete and convenient way to stay on top of your systems is to enroll in one of our service agreement programmes.
Our maintenance services include Calibration, Planned Preventative Maintenance, Repair, Corrective Maintenance, Telephone Support and Consultancy Support.
Calibration Interval
GMP systems require a calibration re-qualification at twelve-month intervals as a minimum requirement. Many customers increase this and add a calibration-only visit at six months as well as a full planned Preventative Maintenance (PM) visit at twelve months.
Preventative Maintenance (PM)
Planned Preventative Maintenance (PM) helps ensure the continued optimal performance of your process scale chromatography equipment. We carry out scheduled maintenance in accordance with cGMP compliant PM protocols written specifically for your equipment. As standard, iLab engineers:
- Replace all wear parts to ensure consistent process performance.
- Verify calibration with tools which are referenced to national standards.
- Perform a system inspection to anticipate any possible risk of failure.
- Conduct comprehensive functional tests to demonstrate and document that the equipment is in full and proper working order.
We’ll replace some parts as standard, regardless of condition, as part of an annual PM procedure. This will enhance the reliability of your process scale chromatography systems and reduce the risk of failure during production runs. We recommend that the following parts are routinely replaced as part of your planned process scale maintenance, and we include this as part of your annual agreement:
- Valve diaphragms
- Sanitary seals
- Other seals and O rings
- Pump seals, check valves and diaphragms
- pH electrodes
- Batteries
Breakdown, Repair & Corrective Maintenance
Equipment, when correctly designed and installed, should operate successfully without problems. However, even the best system may be affected by unpredictable events. This could be variations in the quality of the process fluid or environmental factors and could lead to system failure – often at the most critical time.
Such events can cause costly down time or even loss of a production batch. Should you be faced with such a situation, iLab Solutions Service Engineers will assist your recovery and return your system to full operation, as quickly as possible.
Older systems will have a greater risk of failure or use obsolete components which become difficult to source as spare parts. iLab Solutions have great success sourcing obsolete parts and if not, we can recommend and provide alternatives.
Equipment Covered
We service a variety of makes and models of PSC systems, including:
AKTA Classic Pilot / Pilot 600 / Process
For all other makes and models, please enquire.
